Jun-Gyu Park Selected Research

K-18 conjugate (K18)

12/2022	The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus.
1/2022	Animal Models of COVID-19: Transgenic Mouse Model.
11/2021	Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2.
10/2021	A Bifluorescent-Based Assay for the Identification of Neutralizing Antibodies against SARS-CoV-2 Variants of Concern In Vitro and In Vivo.
10/2021	Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice.
11/2020	Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice.

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Jun-Gyu Park Research Topics

Disease

24	Infections 12/2022 - 09/2013
17	COVID-19 12/2022 - 01/2020
9	Virus Diseases (Viral Diseases) 01/2022 - 01/2020
5	Neoplasms (Cancer) 03/2022 - 12/2019
5	Human Influenza (Influenza) 05/2021 - 01/2020
5	Diarrhea 01/2019 - 09/2010
3	Severe Acute Respiratory Syndrome 06/2021 - 01/2020
3	Zika Virus Infection 01/2020 - 01/2019
2	Necrosis 12/2022 - 06/2012
2	Body Weight (Weight, Body) 01/2022 - 06/2014
2	Cytokine Release Syndrome 01/2022 - 11/2020
2	Inflammation (Inflammations) 09/2021 - 12/2012
2	Rotavirus Infections 01/2019 - 01/2018
2	Gastroenteritis 01/2019 - 12/2018
1	Disease Progression 12/2022
1	Smallpox (Variola) 12/2021
1	Hypoxia (Hypoxemia) 01/2021
1	Triple Negative Breast Neoplasms 01/2021
1	Herpesviridae Infections (Herpesvirus Infection) 01/2020
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 12/2019
1	Pituitary ACTH Hypersecretion 12/2019
1	Viremia 09/2013

Drug/Important Bio-Agent (IBA)

14	Antiviral Agents (Antivirals)IBA 12/2022 - 12/2012
14	VaccinesIBA 01/2022 - 01/2019
9	Proteins (Proteins, Gene)FDA Link 12/2022 - 02/2017
6	K-18 conjugate (K18)IBA 12/2022 - 11/2020
5	Monoclonal AntibodiesIBA 01/2022 - 01/2020
5	Angiotensin-Converting Enzyme 2IBA 01/2022 - 11/2020
3	Sialic AcidsIBA 01/2019 - 06/2014
3	CarbohydratesIBA 01/2018 - 06/2014
3	Messenger RNA (mRNA)IBA 02/2017 - 06/2012
2	Phosphotransferases (Kinase)IBA 12/2022 - 01/2022
2	Keratin-18 (Keratin 18)IBA 12/2022 - 01/2022
2	Small Interfering RNA (siRNA)IBA 01/2022 - 09/2018
2	EnzymesIBA 01/2022 - 01/2018
2	ChemokinesIBA 01/2022 - 11/2020
2	CytokinesIBA 01/2022 - 12/2012
2	LuciferasesIBA 12/2021 - 01/2021
2	Glycoproteins (Glycoprotein)IBA 10/2021 - 01/2021
2	Blood Group Antigens (Blood Groups)IBA 01/2019 - 04/2016
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2018 - 01/2018
2	Dinoprostone (PGE2)FDA Link 01/2018 - 02/2017
2	N-Acetylneuraminic Acid (Sialic Acid)IBA 04/2016 - 06/2014
1	Protein Kinases (Protein Kinase)IBA 12/2022
1	AntigensIBA 03/2022
1	Cancer VaccinesIBA 03/2022
1	TCF Transcription FactorsIBA 03/2022
1	Sunitinib (Sutent)FDA Link 01/2022
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2022
1	ImmunosorbentsIBA 01/2022
1	Biological Warfare AgentsIBA 12/2021
1	AntibodiesIBA 10/2021
1	Attenuated VaccinesIBA 10/2021
1	oleandrinIBA 06/2021
1	CBLC137IBA 04/2021
1	Photosensitizing Agents (Photosensitizers)IBA 01/2021
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2021
1	phthalocyanineIBA 01/2021
1	ProdrugsIBA 01/2021
1	AQ4NIBA 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	AlbuminsIBA 01/2021
1	Essential Amino AcidsIBA 01/2021
1	Immunoglobulin M (IgM)IBA 01/2021
1	Neutralizing AntibodiesIBA 01/2021
1	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2020
1	Phosphopyruvate Hydratase (Enolase)IBA 12/2019
1	Chromogranin AIBA 12/2019
1	SynaptophysinIBA 12/2019
1	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2019
1	IntegrinsIBA 01/2019
1	LigandsIBA 01/2019
1	Claudin-1IBA 01/2019
1	Tight Junction ProteinsIBA 01/2019
1	OccludinIBA 01/2019
1	CholesterolIBA 09/2018
1	CyclodextrinsIBA 09/2018
1	Pharmaceutical PreparationsIBA 09/2018
1	GTP Phosphohydrolases (GTPases)IBA 09/2018
1	Dynamins (Dynamin)IBA 09/2018
1	Dynamin IIIBA 09/2018
1	N'- (3,4- dihydroxybenzylidene)- 3- hydroxy- 2- naphthahydrazideIBA 09/2018
1	Nystatin (Mycostatin)FDA LinkGeneric 09/2018
1	ClathrinIBA 09/2018
1	Chlorpromazine (Thorazine)FDA Link 09/2018
1	Adenosine Triphosphatases (ATPase)IBA 01/2018
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 02/2017
1	GangliosidesIBA 04/2016
1	GlycolipidsIBA 04/2016
1	GD1a gangliosideIBA 04/2016
1	Peptide Hydrolases (Proteases)FDA Link 06/2014
1	Neuraminidase (Sialidase)IBA 06/2014
1	LectinsIBA 06/2014
1	Viral RNAIBA 09/2013

Therapy/Procedure

10	Therapeutics 12/2022 - 12/2012
2	Immunotherapy 01/2022 - 01/2021
1	Oncolytic Virotherapy 03/2022
1	Anesthesia 01/2022
1	Intravenous Injections 01/2021
1	Photochemotherapy (Photodynamic Therapy) 01/2021